Travelan® Progresses to Phase 3 Trials: Positive Results Show Promise

Mar 07, 2024

Immuron Limited (ASX: IMC) advances Travelan® to Phase 3 trials with FDA support, based on successful Phase 2 results. Administered once daily, Travelan® demonstrated efficacy against ETEC-induced diarrhea, with a 36.4% reduction in moderate to severe cases compared to placebo. Additionally, Travelan® showed a 66.7% reduction in severe diarrhea and an 83.3% decrease in early antibiotic treatment requirement. Notably, all subjects needing IV fluids were in the placebo group.

Despite a lower-than-expected attack rate, the study proved Travelan® 's efficacy. Immuron plans Phase 3 trials and FDA discussions for Travelan®'s prophylactic use against Travelers’ Diarrhea. These findings underscore Travelan®'s potential as a preventive measure against infectious enteric diseases, particularly significant for the US military. Further research will explore optimal dosing regimens.

 

 

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