Imugene’s VAXINIA MAST trial progressed with first patient dosed

Mar 03, 2023

Imugene Limited (ASX: IMU) has reported that the Phase 1 MAST study, evaluating the safety of its novel cancer-killing virus CF33-hNIS (VAXINIA), has commenced. The trial will investigate the efficacy of the virus in patients with metastatic or advanced solid tumours who have undergone at least two previous lines of standard care treatment. The study will consist of low doses of VAXINIA, delivered to patients via intratumoral or intravenous means, and Pembrolizumab, a well-known drug, in combination.

The study will be conducted in approximately 10 trial sites across the United States and Australia, with a total of 100 patients expected to participate. The trial aims to identify VAXINIA's potential benefits when used in combination with Pembrolizumab. Imugene CEO Leslie Chong stated that the trial was progressing at an excellent pace and looked forward to data and results in the future.

 

 

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